A random mutation capture assay to detect genomic point mutations in mouse tissue

Herein, a detailed protocol for a random mutation capture (RMC) assay to measure nuclear point mutation frequency in mouse tissue is described. This protocol is a simplified version of the original method developed for human tissue that is easier to perform, yet retains a high sensitivity of detecti...

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Detalles Bibliográficos
Autores principales: Wright, Jocelyn H., Modjeski, Kristina L., Bielas, Jason H., Preston, Bradley D., Fausto, Nelson, Loeb, Lawrence A., Campbell, Jean S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113589/
https://www.ncbi.nlm.nih.gov/pubmed/21459851
http://dx.doi.org/10.1093/nar/gkr142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113589/
https://www.ncbi.nlm.nih.gov/pubmed/21459851
http://dx.doi.org/10.1093/nar/gkr142

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