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Correction of PCR-bias in quantitative DNA methylation studies by means of cubic polynomial regression
DNA methylation profiling has become an important aspect of biomedical molecular analysis. Polymerase chain reaction (PCR) amplification of bisulphite-treated DNA is a processing step that is common to many currently used methods of quantitative methylation analysis. Preferential amplification of un...
Autores principales: | Moskalev, Evgeny A., Zavgorodnij, Mikhail G., Majorova, Svetlana P., Vorobjev, Ivan A., Jandaghi, Pouria, Bure, Irina V., Hoheisel, Jörg D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113592/ https://www.ncbi.nlm.nih.gov/pubmed/21486748 http://dx.doi.org/10.1093/nar/gkr213 |
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