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Correction of PCR-bias in quantitative DNA methylation studies by means of cubic polynomial regression

DNA methylation profiling has become an important aspect of biomedical molecular analysis. Polymerase chain reaction (PCR) amplification of bisulphite-treated DNA is a processing step that is common to many currently used methods of quantitative methylation analysis. Preferential amplification of un...

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Detalles Bibliográficos
Autores principales: Moskalev, Evgeny A., Zavgorodnij, Mikhail G., Majorova, Svetlana P., Vorobjev, Ivan A., Jandaghi, Pouria, Bure, Irina V., Hoheisel, Jörg D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113592/
https://www.ncbi.nlm.nih.gov/pubmed/21486748
http://dx.doi.org/10.1093/nar/gkr213