IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides

The airway epithelium forms a barrier against infection but also produces antimicrobial peptides (AMPs) and other inflammatory mediators to activate the immune system. It has been shown that in allergic disorders, Th2 cytokines may hamper the antimicrobial activity of the epithelium. However, the pr...

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Detalles Bibliográficos
Autores principales: Zuyderduyn, Suzanne, Ninaber, Dennis K, Schrumpf , Jasmijn A, van Sterkenburg, Marianne AJA, Verhoosel, Renate M, Prins, Frans A, van Wetering, Sandra, Rabe, Klaus F, Hiemstra, Pieter S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113720/
https://www.ncbi.nlm.nih.gov/pubmed/21529380
http://dx.doi.org/10.1186/1465-9921-12-59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113720/
https://www.ncbi.nlm.nih.gov/pubmed/21529380
http://dx.doi.org/10.1186/1465-9921-12-59

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