Regulation of hypoxia inducible factor-1α expression by the alteration of redox status in HepG2 cells

Hypoxia inducible factor-1 (HIF-1) has been considered as a critical transcriptional factor in response to hypoxia. It can increase P-glycoprotein (P-Gp) thus generating the resistant effect to chemotherapy. At present, the mechanism regulating HIF-1α is still not fully clear in hypoxic tumor cells....

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Detalles Bibliográficos
Autores principales: Jin, Wen-sen, Kong, Zhao-lu, Shen, Zhi-fen, Jin, Yi-zun, Zhang, Wu-kui, Chen, Guang-fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113749/
https://www.ncbi.nlm.nih.gov/pubmed/21595915
http://dx.doi.org/10.1186/1756-9966-30-61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113749/
https://www.ncbi.nlm.nih.gov/pubmed/21595915
http://dx.doi.org/10.1186/1756-9966-30-61

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