Olanzapine-Induced Hyperphagia and Weight Gain Associate with Orexigenic Hypothalamic Neuropeptide Signaling without Concomitant AMPK Phosphorylation

The success of antipsychotic drug treatment in patients with schizophrenia is limited by the propensity of these drugs to induce hyperphagia, weight gain and other metabolic disturbances, particularly evident for olanzapine and clozapine. However, the molecular mechanisms involved in antipsychotic-i...

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Detalles Bibliográficos
Autores principales: Fernø, Johan, Varela, Luis, Skrede, Silje, Vázquez, María Jesús, Nogueiras, Rubén, Diéguez, Carlos, Vidal-Puig, Antonio, Steen, Vidar M., López, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113797/
https://www.ncbi.nlm.nih.gov/pubmed/21695181
http://dx.doi.org/10.1371/journal.pone.0020571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113797/
https://www.ncbi.nlm.nih.gov/pubmed/21695181
http://dx.doi.org/10.1371/journal.pone.0020571

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