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CD1d-Expressing Breast Cancer Cells Modulate NKT Cell-Mediated Antitumor Immunity in a Murine Model of Breast Cancer Metastasis

BACKGROUND: Tumor tolerance and immune suppression remain formidable obstacles to the efficacy of immunotherapies that harness the immune system to eradicate breast cancer. A novel syngeneic mouse model of breast cancer metastasis was developed in our lab to investigate mechanisms of immune regulati...

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Detalles Bibliográficos
Autores principales: Hix, Laura M., Shi, Yihui H., Brutkiewicz, Randy R., Stein, Paul L., Wang, Chyung-Ru, Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113806/
https://www.ncbi.nlm.nih.gov/pubmed/21695190
http://dx.doi.org/10.1371/journal.pone.0020702