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ShoRAH: estimating the genetic diversity of a mixed sample from next-generation sequencing data

BACKGROUND: With next-generation sequencing technologies, experiments that were considered prohibitive only a few years ago are now possible. However, while these technologies have the ability to produce enormous volumes of data, the sequence reads are prone to error. This poses fundamental hurdles...

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Detalles Bibliográficos
Autores principales: Zagordi, Osvaldo, Bhattacharya, Arnab, Eriksson, Nicholas, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113935/
https://www.ncbi.nlm.nih.gov/pubmed/21521499
http://dx.doi.org/10.1186/1471-2105-12-119