ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites

BACKGROUND: Zinc Finger Nucleases (ZFNs) are man-made restriction enzymes useful for manipulating genomes by cleaving target DNA sequences. ZFNs allow therapeutic gene correction or creation of genetically modified model organisms. ZFN specificity is not absolute; therefore, it is essential to selec...

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Detalles Bibliográficos
Autores principales: Cradick, Thomas J, Ambrosini, Giovanna, Iseli, Christian, Bucher, Philipp, McCaffrey, Anton P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113941/
https://www.ncbi.nlm.nih.gov/pubmed/21569489
http://dx.doi.org/10.1186/1471-2105-12-152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113941/
https://www.ncbi.nlm.nih.gov/pubmed/21569489
http://dx.doi.org/10.1186/1471-2105-12-152

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