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Comparison of three tests of homogeneity of odds ratios in multicenter trials with unequal sample sizes within and among centers

BACKGROUND: Mixed effects logistic models have become a popular method for analyzing multicenter clinical trials with binomial data. However, the statistical properties of these models for testing homogeneity of odds ratios under various conditions, such as within-center and among-centers inequality...

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Detalles Bibliográficos
Autores principales: Bagheri, Zahra, Ayatollahi, Seyyed Mohammad Taghi, Jafari, Peyman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114016/
https://www.ncbi.nlm.nih.gov/pubmed/21518458
http://dx.doi.org/10.1186/1471-2288-11-58