Molecular Dynamics Simulations of Viral RNA Polymerases Link Conserved and Correlated Motions of Functional Elements to Fidelity

The viral RNA-dependent RNA polymerase (RdRp) is essential for multiplication of all RNA viruses. The sequence diversity of an RNA virus population contributes to its ability to infect the host. This diversity emanates from errors made by the RdRp during RNA synthesis. The physical basis for RdRp fi...

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Detalles Bibliográficos
Autores principales: Moustafa, Ibrahim M., Shen, Hujun, Morton, Brandon, Colina, Coray M., Cameron, Craig E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114172/
https://www.ncbi.nlm.nih.gov/pubmed/21575642
http://dx.doi.org/10.1016/j.jmb.2011.04.078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114172/
https://www.ncbi.nlm.nih.gov/pubmed/21575642
http://dx.doi.org/10.1016/j.jmb.2011.04.078

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