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IL28B genetic variations are associated with high sustained virological response (SVR) of interferon-α plus ribavirin therapy in Taiwanese chronic HCV infection

Chronic hepatitis C virus (HCV) infection patients exhibit different sustained virological responses (SVRs) following the treatment with pegylated interferon-α (IFN-α) and ribavirin. Genome-wide association studies consistently linked SVR of IFN-α-based therapy to the IL28B single-nucleotide polymor...

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Detalles Bibliográficos
Autores principales: Chen, J-Y, Lin, C-Y, Wang, C-M, Lin, Y-T, Kuo, S-N, Shiu, C-F, Chang, S-W, Wu, J, Sheen, I-S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114195/
https://www.ncbi.nlm.nih.gov/pubmed/21346780
http://dx.doi.org/10.1038/gene.2011.1