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Nitric Oxide Synthase Inhibitor Improves De Novo and Long-Term l-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats

Inhibitors of neuronal and endothelial nitric oxide synthase decrease l-3,4-dihidroxifenilalanine (l-DOPA)-induced dyskinesias in rodents. The mechanism of nitric oxide inhibitor action is unknown. The aims of the present study were to investigate the decrease of l-DOPA-induced abnormal involuntary...

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Detalles Bibliográficos
Autores principales: Padovan-Neto, Fernando Eduardo, Echeverry, Marcela Bermúdez, Chiavegatto, Silvana, Del-Bel, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114204/
https://www.ncbi.nlm.nih.gov/pubmed/21713068
http://dx.doi.org/10.3389/fnsys.2011.00040