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Age of Islet Autoantibody Appearance and Mean Levels of Insulin, but Not GAD or IA-2 Autoantibodies, Predict Age of Diagnosis of Type 1 Diabetes: Diabetes Autoimmunity Study in the Young

OBJECTIVE: We evaluated predictors of progression to diabetes in children with high-risk HLA genotypes and persistent islet autoantibodies. RESEARCH DESIGN AND METHODS: The Diabetes Autoimmunity Study in the Young (DAISY) followed 2,542 children with autoantibodies measured to GAD, IA-2, and insulin...

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Detalles Bibliográficos
Autores principales: Steck, Andrea K., Johnson, Kelly, Barriga, Katherine J., Miao, Dongmei, Yu, Liping, Hutton, John C., Eisenbarth, George S., Rewers, Marian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114355/
https://www.ncbi.nlm.nih.gov/pubmed/21562325
http://dx.doi.org/10.2337/dc10-2088