Altered Skeletal Muscle Lipase Expression and Activity Contribute to Insulin Resistance in Humans

OBJECTIVE: Insulin resistance is associated with elevated content of skeletal muscle lipids, including triacylglycerols (TAGs) and diacylglycerols (DAGs). DAGs are by-products of lipolysis consecutive to TAG hydrolysis by adipose triglyceride lipase (ATGL) and are subsequently hydrolyzed by hormone-...

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Detalles Bibliográficos
Autores principales: Badin, Pierre-Marie, Louche, Katie, Mairal, Aline, Liebisch, Gerhard, Schmitz, Gerd, Rustan, Arild C., Smith, Steven R., Langin, Dominique, Moro, Cedric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114384/
https://www.ncbi.nlm.nih.gov/pubmed/21498783
http://dx.doi.org/10.2337/db10-1364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114384/
https://www.ncbi.nlm.nih.gov/pubmed/21498783
http://dx.doi.org/10.2337/db10-1364

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