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Altered Skeletal Muscle Lipase Expression and Activity Contribute to Insulin Resistance in Humans
OBJECTIVE: Insulin resistance is associated with elevated content of skeletal muscle lipids, including triacylglycerols (TAGs) and diacylglycerols (DAGs). DAGs are by-products of lipolysis consecutive to TAG hydrolysis by adipose triglyceride lipase (ATGL) and are subsequently hydrolyzed by hormone-...
Autores principales: | Badin, Pierre-Marie, Louche, Katie, Mairal, Aline, Liebisch, Gerhard, Schmitz, Gerd, Rustan, Arild C., Smith, Steven R., Langin, Dominique, Moro, Cedric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114384/ https://www.ncbi.nlm.nih.gov/pubmed/21498783 http://dx.doi.org/10.2337/db10-1364 |
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