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IL-13Rα1 Expression on β-Cell–Specific T Cells in NOD Mice

OBJECTIVE: Immunotherapy using peptides from the β-cell antigen GAD65 can preserve glucose homeostasis in diabetes-prone NOD mice; however, the precise mechanisms that arrest islet-reactive T cells remain unresolved. Our previous work revealed that a dominant GAD65 epitope contained two overlapping...

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Detalles Bibliográficos
Autores principales: Rasche, Sarah S., Phillips, Michele, McInerney, Marcia F., Sercarz, Eli E., Quinn, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114389/
https://www.ncbi.nlm.nih.gov/pubmed/21617187
http://dx.doi.org/10.2337/db10-1229