Diabetic Visceral Hypersensitivity Is Associated With Activation of Mitogen-Activated Kinase in Rat Dorsal Root Ganglia

OBJECTIVE: Diabetic patients often experience visceral hypersensitivity and anorectal dysfunction. We hypothesize that the enhanced excitability of colon projecting dorsal root ganglia (DRG) neurons observed in diabetes is caused by a decrease in the amplitude of the transient A-type K(+) (I(A)) cur...

Descripción completa

Detalles Bibliográficos
Autores principales: Grabauskas, Gintautas, Heldsinger, Andrea, Wu, Xiaoyin, Xu, Dabo, Zhou, ShiYi, Owyang, Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114390/
https://www.ncbi.nlm.nih.gov/pubmed/21515848
http://dx.doi.org/10.2337/db10-1507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114390/
https://www.ncbi.nlm.nih.gov/pubmed/21515848
http://dx.doi.org/10.2337/db10-1507

Ejemplares similares