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Diabetic Visceral Hypersensitivity Is Associated With Activation of Mitogen-Activated Kinase in Rat Dorsal Root Ganglia

OBJECTIVE: Diabetic patients often experience visceral hypersensitivity and anorectal dysfunction. We hypothesize that the enhanced excitability of colon projecting dorsal root ganglia (DRG) neurons observed in diabetes is caused by a decrease in the amplitude of the transient A-type K(+) (I(A)) cur...

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Detalles Bibliográficos
Autores principales:	Grabauskas, Gintautas, Heldsinger, Andrea, Wu, Xiaoyin, Xu, Dabo, Zhou, ShiYi, Owyang, Chung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114390/ https://www.ncbi.nlm.nih.gov/pubmed/21515848 http://dx.doi.org/10.2337/db10-1507

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