Dedifferentiation of Immortalized Human Podocytes in Response to Transforming Growth Factor-β: A Model for Diabetic Podocytopathy

OBJECTIVE: Diabetic nephropathy is associated with dedifferentiation of podocytes, losing the specialized features required for efficient glomerular function and acquiring a number of profibrotic, proinflammatory, and proliferative features. These result from tight junction and cytoskeletal rearrang...

Descripción completa

Detalles Bibliográficos
Autores principales: Herman-Edelstein, Michal, Thomas, Merlin C., Thallas-Bonke, Vicki, Saleem, Moin, Cooper, Mark E., Kantharidis, Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114395/
https://www.ncbi.nlm.nih.gov/pubmed/21521871
http://dx.doi.org/10.2337/db10-1110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114395/
https://www.ncbi.nlm.nih.gov/pubmed/21521871
http://dx.doi.org/10.2337/db10-1110

Ejemplares similares