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Decreased Cerebrovascular Brain-Derived Neurotrophic Factor–Mediated Neuroprotection in the Diabetic Brain
OBJECTIVE: Diabetes is an independent risk factor for stroke. However, the underlying mechanism of how diabetes confers that this risk is not fully understood. We hypothesize that secretion of neurotrophic factors by the cerebral endothelium, such as brain-derived neurotrophic factor (BDNF), is supp...
Autores principales: | Navaratna, Deepti, Guo, Shu-zhen, Hayakawa, Kazhuhide, Wang, Xiaoying, Gerhardinger, Chiara, Lo, Eng H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114398/ https://www.ncbi.nlm.nih.gov/pubmed/21562076 http://dx.doi.org/10.2337/db10-1371 |
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