Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice

OBJECTIVE: Autophagy is a critical cellular system for removal of aggregated proteins and damaged organelles. Although dysregulated autophagy is implicated in the development of heart failure, the role of autophagy in the development of diabetic cardiomyopathy has not been studied. We investigated w...

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Detalles Bibliográficos
Autores principales: Xie, Zhonglin, Lau, Kai, Eby, Bonnie, Lozano, Pedro, He, Chaoyong, Pennington, Becky, Li, Hongliang, Rathi, Shradha, Dong, Yunzhou, Tian, Rong, Kem, David, Zou, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114402/
https://www.ncbi.nlm.nih.gov/pubmed/21562078
http://dx.doi.org/10.2337/db10-0351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114402/
https://www.ncbi.nlm.nih.gov/pubmed/21562078
http://dx.doi.org/10.2337/db10-0351

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