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Sequencing and Analysis of JC Virus DNA From Natalizumab-Treated PML Patients

Background. Progressive multifocal leukoencephalopathy (PML) in natalizumab-treated MS patients is linked to JC virus (JCV) infection. JCV sequence variation and rearrangements influence viral pathogenicity and tropism. To better understand PML development, we analyzed viral DNA sequences in blood,...

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Detalles Bibliográficos
Autores principales: Reid, Carl E., Li, Huo, Sur, Gargi, Carmillo, Paul, Bushnell, Steven, Tizard, Rich, McAuliffe, Michele, Tonkin, Christopher, Simon, Kenneth, Goelz, Susan, Cinque, Paola, Gorelik, Leonid, Carulli, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114470/
https://www.ncbi.nlm.nih.gov/pubmed/21673034
http://dx.doi.org/10.1093/infdis/jir256