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TP53 Status and Response to Treatment in Breast Cancers

The p53 wild-type protein plays an important role in cells as is shown by its fine regulation at different levels. Since its discovery, numerous mutations have been described. In breast cancers, p53 is mutated in almost 30% of cases, with a higher frequency in some tumor subtypes. TP53 mutation is r...

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Detalles Bibliográficos
Autores principales: Varna, Mariana, Bousquet, Guilhem, Plassa, Louis-François, Bertheau, Philippe, Janin, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114547/
https://www.ncbi.nlm.nih.gov/pubmed/21760703
http://dx.doi.org/10.1155/2011/284584