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Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells

Regulation of RNA levels is determined through the interplay between RNA production, processing and degradation. However, since most global studies of RNA regulation do not distinguish the separate contributions of these processes, relatively little is known about how they are temporally integrated...

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Detalles Bibliográficos
Autores principales: Rabani, Michal, Levin, Joshua Z, Fan, Lin, Adiconis, Xian, Raychowdhury, Raktima, Garber, Manuel, Gnirke, Andreas, Nusbaum, Chad, Hacohen, Nir, Friedman, Nir, Amit, Ido, Regev, Aviv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114636/
https://www.ncbi.nlm.nih.gov/pubmed/21516085
http://dx.doi.org/10.1038/nbt.1861