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Identification of models of heterogeneous cell populations from population snapshot data

BACKGROUND: Most of the modeling performed in the area of systems biology aims at achieving a quantitative description of the intracellular pathways within a "typical cell". However, in many biologically important situations even clonal cell populations can show a heterogeneous response. T...

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Detalles Bibliográficos
Autores principales: Hasenauer, Jan, Waldherr, Steffen, Doszczak, Malgorzata, Radde, Nicole, Scheurich, Peter, Allgöwer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114742/
https://www.ncbi.nlm.nih.gov/pubmed/21527025
http://dx.doi.org/10.1186/1471-2105-12-125