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Identification of Peptide Mimotopes of Trypanosoma brucei gambiense Variant Surface Glycoproteins

BACKGROUND: The current antibody detection tests for the diagnosis of gambiense human African trypanosomiasis (HAT) are based on native variant surface glycoproteins (VSGs) of Trypanosoma brucei (T.b.) gambiense. These native VSGs are difficult to produce, and contain non-specific epitopes that may...

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Detalles Bibliográficos
Autores principales: Van Nieuwenhove, Liesbeth Carolien, Rogé, Stijn, Balharbi, Fatima, Dieltjens, Tessa, Laurent, Thierry, Guisez, Yves, Büscher, Philippe, Lejon, Veerle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114753/
https://www.ncbi.nlm.nih.gov/pubmed/21695105
http://dx.doi.org/10.1371/journal.pntd.0001189