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Premitotic Assembly of Human CENPs -T and -W Switches Centromeric Chromatin to a Mitotic State

Centromeres are differentiated chromatin domains, present once per chromosome, that direct segregation of the genome in mitosis and meiosis by specifying assembly of the kinetochore. They are distinct genetic loci in that their identity in most organisms is determined not by the DNA sequences they a...

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Detalles Bibliográficos
Autores principales: Prendergast, Lisa, van Vuuren, Chelly, Kaczmarczyk, Agnieszka, Doering, Volker, Hellwig, Daniela, Quinn, Nadine, Hoischen, Christian, Diekmann, Stephan, Sullivan, Kevin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114758/
https://www.ncbi.nlm.nih.gov/pubmed/21695110
http://dx.doi.org/10.1371/journal.pbio.1001082