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Towards a Pharmacophore for Amyloid
Diagnosing and treating Alzheimer's and other diseases associated with amyloid fibers remains a great challenge despite intensive research. To aid in this effort, we present atomic structures of fiber-forming segments of proteins involved in Alzheimer's disease in complex with small molecu...
Autores principales: | Landau, Meytal, Sawaya, Michael R., Faull, Kym F., Laganowsky, Arthur, Jiang, Lin, Sievers, Stuart A., Liu, Jie, Barrio, Jorge R., Eisenberg, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114762/ https://www.ncbi.nlm.nih.gov/pubmed/21695112 http://dx.doi.org/10.1371/journal.pbio.1001080 |
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