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Therapeutic concentrations of glucagon-like peptide-1 in cerebrospinal fluid following cell-based delivery into the cerebral ventricles of cats

BACKGROUND: Neuropeptides may have considerable potential in the treatment of acute and chronic neurological diseases. Encapsulated genetically engineered cells have been suggested as a means for sustained local delivery of such peptides to the brain. In our experiments, we studied human mesenchymal...

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Detalles Bibliográficos
Autores principales: Glage, Silke, Klinge, Petra M, Miller, Miles C, Wallrapp, Christine, Geigle, Peter, Hedrich, Hans J, Brinker, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114785/
https://www.ncbi.nlm.nih.gov/pubmed/21575271
http://dx.doi.org/10.1186/2045-8118-8-18