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Drosophila Melanogaster as a Model System for Studies of Islet Amyloid Polypeptide Aggregation
BACKGROUND: Recent research supports that aggregation of islet amyloid polypeptide (IAPP) leads to cell death and this makes islet amyloid a plausible cause for the reduction of beta cell mass, demonstrated in patients with type 2 diabetes. IAPP is produced by the beta cells as a prohormone, and pro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114789/ https://www.ncbi.nlm.nih.gov/pubmed/21695120 http://dx.doi.org/10.1371/journal.pone.0020221 |