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Drosophila Melanogaster as a Model System for Studies of Islet Amyloid Polypeptide Aggregation

BACKGROUND: Recent research supports that aggregation of islet amyloid polypeptide (IAPP) leads to cell death and this makes islet amyloid a plausible cause for the reduction of beta cell mass, demonstrated in patients with type 2 diabetes. IAPP is produced by the beta cells as a prohormone, and pro...

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Detalles Bibliográficos
Autores principales:	Schultz, Sebastian Wolfgang, Nilsson, K. Peter R., Westermark, Gunilla Torstensdotter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114789/ https://www.ncbi.nlm.nih.gov/pubmed/21695120 http://dx.doi.org/10.1371/journal.pone.0020221

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