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Segregation of point mutation heteroplasmy in the control region of dog mtDNA studied systematically in deep generation pedigrees

Heteroplasmy, the presence of two or more variants in an organism, may render mitochondrial DNA (mtDNA)-based individual identification challenging in forensic analysis. However, the variation of heteroplasmic proportions and the segregation of heteroplasmic variants through generations and within f...

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Detalles Bibliográficos
Autores principales: Klütsch, Cornelya F. C., Seppälä, Eija H., Uhlén, Mathias, Lohi, Hannes, Savolainen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115052/
https://www.ncbi.nlm.nih.gov/pubmed/21049272
http://dx.doi.org/10.1007/s00414-010-0524-7