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RNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding
Cytokines, such as interferons, erythropoietin, leptin and most interleukins, signal through type 1 cytokine receptors and activate the canonical JAK–STAT pathway. Aberrant cytokine signalling underlies numerous pathologies and adequate, temporary receptor activation is therefore under tight control...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Company of Biologists
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115735/ https://www.ncbi.nlm.nih.gov/pubmed/21378310 http://dx.doi.org/10.1242/jcs.078055 |