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RNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding

Cytokines, such as interferons, erythropoietin, leptin and most interleukins, signal through type 1 cytokine receptors and activate the canonical JAK–STAT pathway. Aberrant cytokine signalling underlies numerous pathologies and adequate, temporary receptor activation is therefore under tight control...

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Detalles Bibliográficos
Autores principales:	Wauman, Joris, De Ceuninck, Leentje, Vanderroost, Nele, Lievens, Sam, Tavernier, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Company of Biologists 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115735/ https://www.ncbi.nlm.nih.gov/pubmed/21378310 http://dx.doi.org/10.1242/jcs.078055

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