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PDZ-RhoGEF ubiquitination by Cullin3–KLHL20 controls neurotrophin-induced neurite outgrowth

The induction of neurite outgrowth and arborization is critical for developmental and regenerative processes. In this paper, we report that the BTB-kelch protein KLHL20 promoted neurite outgrowth and arborization in hippocampal and cortical neurons through its interaction with Cullin3 to form a ubiq...

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Detalles Bibliográficos
Autores principales: Lin, Mei-Yao, Lin, Yu-Min, Kao, Te-chan, Chuang, Hsiang-Hao, Chen, Ruey-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115788/
https://www.ncbi.nlm.nih.gov/pubmed/21670212
http://dx.doi.org/10.1083/jcb.201103015