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The cortical protein Lte1 promotes mitotic exit by inhibiting the spindle position checkpoint kinase Kin4

The spindle position checkpoint (SPOC) is an essential surveillance mechanism that allows mitotic exit only when the spindle is correctly oriented along the cell axis. Key SPOC components are the kinase Kin4 and the Bub2–Bfa1 GAP complex that inhibit the mitotic exit–promoting GTPase Tem1. During an...

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Detalles Bibliográficos
Autores principales: Bertazzi, Daniela Trinca, Kurtulmus, Bahtiyar, Pereira, Gislene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115795/
https://www.ncbi.nlm.nih.gov/pubmed/21670215
http://dx.doi.org/10.1083/jcb.201101056