Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication

Treslin, a TopBP1-interacting protein, is necessary for deoxyribonucleic acid (DNA) replication in vertebrates. Association between Treslin and TopBP1 requires cyclin-dependent kinase (Cdk) activity in Xenopus laevis egg extracts. We investigated the mechanism and functional importance of Cdk for th...

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Detalles Bibliográficos
Autores principales: Kumagai, Akiko, Shevchenko, Anna, Shevchenko, Andrej, Dunphy, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115804/
https://www.ncbi.nlm.nih.gov/pubmed/21646402
http://dx.doi.org/10.1083/jcb.201102003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115804/
https://www.ncbi.nlm.nih.gov/pubmed/21646402
http://dx.doi.org/10.1083/jcb.201102003

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