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Protein kinase A-dependent Neuronal Nitric Oxide Synthase Activation Mediates the Enhancement of Baroreflex Response by Adrenomedullin in the Nucleus Tractus Solitarii of Rats

BACKGROUND: Adrenomedullin (ADM) exerts its biological functions through the receptor-mediated enzymatic mechanisms that involve protein kinase A (PKA), or neuronal nitric oxide synthase (nNOS). We previously demonstrated that the receptor-mediated cAMP/PKA pathway involves in ADM-enhanced barorecep...

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Detalles Bibliográficos
Autores principales: Yen, David HT, Chen, Lih-Chi, Shen, Yuh-Chiang, Chiu, Ying-Chen, Ho, I-Chun, Lou, Ya-Jou, Chen, I-Chin, Yen, Jiin-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115842/
https://www.ncbi.nlm.nih.gov/pubmed/21595896
http://dx.doi.org/10.1186/1423-0127-18-32