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Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts
BACKGROUND: Nanoparticles possess several advantages as a carrier system for intracellular delivery of therapeutic agents. Rapamycin is an immunosuppressive agent which also exhibits marked antiproliferative properties. We investigated whether rapamycin-loaded nanoparticles(NPs) can reduce neointima...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115851/ https://www.ncbi.nlm.nih.gov/pubmed/21569412 http://dx.doi.org/10.1186/1749-8090-6-69 |