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Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts

BACKGROUND: Nanoparticles possess several advantages as a carrier system for intracellular delivery of therapeutic agents. Rapamycin is an immunosuppressive agent which also exhibits marked antiproliferative properties. We investigated whether rapamycin-loaded nanoparticles(NPs) can reduce neointima...

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Detalles Bibliográficos
Autores principales: Zou, Junjie, Zhang, Xiwei, Yang, Hongyu, Zhu, Yi, Ma, Hao, Wang, Shui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115851/
https://www.ncbi.nlm.nih.gov/pubmed/21569412
http://dx.doi.org/10.1186/1749-8090-6-69