HMM-FRAME: accurate protein domain classification for metagenomic sequences containing frameshift errors

BACKGROUND: Protein domain classification is an important step in metagenomic annotation. The state-of-the-art method for protein domain classification is profile HMM-based alignment. However, the relatively high rates of insertions and deletions in homopolymer regions of pyrosequencing reads create...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Sun, Yanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115854/
https://www.ncbi.nlm.nih.gov/pubmed/21609463
http://dx.doi.org/10.1186/1471-2105-12-198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115854/
https://www.ncbi.nlm.nih.gov/pubmed/21609463
http://dx.doi.org/10.1186/1471-2105-12-198

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