Synthesis of 86 species of 1,5-diaryl-3-oxo-1,4-pentadienes analogs of curcumin can yield a good lead in vivo

BACKGROUND: Curcumin is known to possess many anti-tumor properties such as inhibition of tumor growth and induction of apotosis. However, limited bioavailability of curcumin prevents its clinical application. A synthesized curcumin analog, 1,5-diaryl-3-oxo-1,4-pentadiene such as GO-Y030, has the im...

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Detalles Bibliográficos
Autores principales: Kudo, Chieko, Yamakoshi, Hiroyuki, Sato, Atsuko, Nanjo, Hiroshi, Ohori, Hisatsugu, Ishioka, Chikashi, Iwabuchi, Yoshiharu, Shibata, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115866/
https://www.ncbi.nlm.nih.gov/pubmed/21619659
http://dx.doi.org/10.1186/1471-2210-11-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115866/
https://www.ncbi.nlm.nih.gov/pubmed/21619659
http://dx.doi.org/10.1186/1471-2210-11-4

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