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Synthesis of 86 species of 1,5-diaryl-3-oxo-1,4-pentadienes analogs of curcumin can yield a good lead in vivo

BACKGROUND: Curcumin is known to possess many anti-tumor properties such as inhibition of tumor growth and induction of apotosis. However, limited bioavailability of curcumin prevents its clinical application. A synthesized curcumin analog, 1,5-diaryl-3-oxo-1,4-pentadiene such as GO-Y030, has the im...

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Detalles Bibliográficos
Autores principales:	Kudo, Chieko, Yamakoshi, Hiroyuki, Sato, Atsuko, Nanjo, Hiroshi, Ohori, Hisatsugu, Ishioka, Chikashi, Iwabuchi, Yoshiharu, Shibata, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115866/ https://www.ncbi.nlm.nih.gov/pubmed/21619659 http://dx.doi.org/10.1186/1471-2210-11-4

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