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Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH

BACKGROUND: A functioning ubiquitin proteasome system (UPS) is essential for a number of diverse cellular processes and maintenance of overall cellular homeostasis. The ability of proteasome inhibitors, such as Velcade, to promote extrinsic apoptotic effects illustrates the importance of the ubiquit...

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Detalles Bibliográficos
Autores principales: Christian, Perry A, Fiandalo, Michael V, Schwarze, Steven R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115909/
https://www.ncbi.nlm.nih.gov/pubmed/21586138
http://dx.doi.org/10.1186/1476-4598-10-57