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Integration of Expressed Sequence Tag Data Flanking Predicted RNA Secondary Structures Facilitates Novel Non-Coding RNA Discovery

Many computational methods have been used to predict novel non-coding RNAs (ncRNAs), but none, to our knowledge, have explicitly investigated the impact of integrating existing cDNA-based Expressed Sequence Tag (EST) data that flank structural RNA predictions. To determine whether flanking EST data...

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Detalles Bibliográficos
Autores principales: Krzyzanowski, Paul M., Price, Feodor D., Muro, Enrique M., Rudnicki, Michael A., Andrade-Navarro, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115948/
https://www.ncbi.nlm.nih.gov/pubmed/21698286
http://dx.doi.org/10.1371/journal.pone.0020561