Conformational Changes of rBTI from Buckwheat upon Binding to Trypsin: Implications for the Role of the P(8)′ Residue in the Potato Inhibitor I Family

BWI-1 (buckwheat trypsin inhibitor), a member of the potato inhibitor I family, suppresses the growth of T-acute lymphoblastic leukemia cells and induces apoptosis in human solid tumor cell lines. Here, we report the crystal structure of rBTI (recombinant buckwheat trypsin inhibitor), a recombinant...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Longfei, Zhao, Fei, Li, Mei, Zhang, Hongmei, Gao, Yu, Cao, Peng, Pan, Xiaowei, Wang, Zhuanhua, Chang, Wenrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115953/
https://www.ncbi.nlm.nih.gov/pubmed/21698291
http://dx.doi.org/10.1371/journal.pone.0020950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115953/
https://www.ncbi.nlm.nih.gov/pubmed/21698291
http://dx.doi.org/10.1371/journal.pone.0020950

Ejemplares similares