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Conformational Changes of rBTI from Buckwheat upon Binding to Trypsin: Implications for the Role of the P(8)′ Residue in the Potato Inhibitor I Family
BWI-1 (buckwheat trypsin inhibitor), a member of the potato inhibitor I family, suppresses the growth of T-acute lymphoblastic leukemia cells and induces apoptosis in human solid tumor cell lines. Here, we report the crystal structure of rBTI (recombinant buckwheat trypsin inhibitor), a recombinant...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115953/ https://www.ncbi.nlm.nih.gov/pubmed/21698291 http://dx.doi.org/10.1371/journal.pone.0020950 |