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Statistical Quantification of Methylation Levels by Next-Generation Sequencing
BACKGROUND/AIMS: Recently, next-generation sequencing-based technologies have enabled DNA methylation profiling at high resolution and low cost. Methyl-Seq and Reduced Representation Bisulfite Sequencing (RRBS) are two such technologies that interrogate methylation levels at CpG sites throughout the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115964/ https://www.ncbi.nlm.nih.gov/pubmed/21698242 http://dx.doi.org/10.1371/journal.pone.0021034 |