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Statistical Quantification of Methylation Levels by Next-Generation Sequencing

BACKGROUND/AIMS: Recently, next-generation sequencing-based technologies have enabled DNA methylation profiling at high resolution and low cost. Methyl-Seq and Reduced Representation Bisulfite Sequencing (RRBS) are two such technologies that interrogate methylation levels at CpG sites throughout the...

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Detalles Bibliográficos
Autores principales: Wu, Guodong, Yi, Nengjun, Absher, Devin, Zhi, Degui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115964/
https://www.ncbi.nlm.nih.gov/pubmed/21698242
http://dx.doi.org/10.1371/journal.pone.0021034