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Shared Epitope Alleles Remain A Risk Factor for Anti-Citrullinated Proteins Antibody (ACPA) – Positive Rheumatoid Arthritis in Three Asian Ethnic Groups

BACKGROUND: To investigate the associations between HLA-DRB1 shared epitope (SE) alleles and rheumatoid arthritis in subsets of rheumatoid arthritis defined by autoantibodies in three Asian populations from Malaysia. METHODS: 1,079 rheumatoid arthritis patients and 1,470 healthy controls were includ...

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Detalles Bibliográficos
Autores principales: Chun-Lai, Too, Padyukov, Leonid, Dhaliwal, Jasbir Singh, Lundström, Emeli, Yahya, Abqariyah, Muhamad, Nor Asiah, Klareskog, Lars, Alfredsson, Lars, Larsson, Per Tobias, Murad, Shahnaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115981/
https://www.ncbi.nlm.nih.gov/pubmed/21698259
http://dx.doi.org/10.1371/journal.pone.0021069